| 1865 | Wilfred Thomason Grenfell born in Parkgate, England, February 28. |
| 1883 | Enters medical school at the London Hospital. |
| 1885 | Inspired by evangelist Dwight Moody to do God’s work. |
| 1886 | Becomes a medical doctor and joins the Royal National Mission to Deep Sea Fishermen. |
| 1892 | Comes to investigate the condition of the fishermen on the Labrador coast. |
| 1893 | Builds first hospital at Battle Harbour, Labrador. |
| 1894 | Grenfell Labrador Medical Mission formed. |
| 1896 | Makes first lecture tour of U.S.A.; starts Red Bay. Co-operative |
| 1900 | Chooses St. Anthony as headquarters for Grenfell Mission; acquires first hospital ship, Strathcona I. |
| 1901 | Establishes co-operative lumber mill at Roddickton. |
| 1905 | Starts orphanage in St. Anthony; Andrew Carnegie donates travelling library. |
| 1906 | Start of Grenfell Industrial Department. |
| 1907 | The Companion of the Most Distinguished Order of St. Michael and St. George presented to Dr. Grenfell. Formation of Grenfell Association of America and Grenfell Association of New England. |
| 1908 | Brings reindeer to Newfoundland from Lapland; adrift on an icepan, Easter Sunday, April 21. |
| 1909 | Establishes non-denominational school at St. Anthony; marries Anne Elizabeth Caldwell MacClanahan on November 18. |
| 1910 | Birth of son, Wilfred Thomason, Jr. |
| 1912 | Formation of International Grenfell Association; birth of son Kinloch Pascoe. |
| 1917 | Birth of daughter, Rosamond Loveday. |
| 1921 | Builds brick orphanage at St. Anthony. |
| 1926 | Formation of Grenfell Association of Great Britain and Northern Ireland; Grenfell has first heart attack. |
| 1927 | Knight Commander of The Order of St. Michael and St. George presented to Dr. Grenfell. New hospital at St. Anthony opens. |
| 1928 | Construction of marine slipway and dry dock in St. Anthony. |
| 1929 | Grenfell has second heart attack. |
| 1931 | Forbes-Grenfell expedition to chart entire Labrador coast |
| 1937 | Grenfell retires as Superintendent. |
| 1938 | Lady Grenfell dies. |
| 1940 | Dr. Grenfell dies. |
| 1978 | Formation of Grenfell Historical Society. |
| 1981 | Grenfell Regional Health Services established. |
| 1992 | The Grenfell Centennial. |
| 1998 | Completion of the Grenfell Masterplan. |